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January 9, 2012 Page 3
La Merie Biologics Vol. 5, Issue 2

Generex to accelerate clinical development of its Her2 cancer vaccine


Generex Biotechnology provided an update to the clinical development & regulatory strategy for its cancer vaccine, AE37. Positive interim Phase 2b clinical data from the study in HER-2 expressing breast cancer subjects has lead to an earlier-than-expected advancement in the overall development of AE37 for both breast and prostate cancer indications. AE37 is a novel Ii-Key Hybrid-based HER-2/neu Peptide Vaccine designed to train the immune system, independent of HLA-type, to track down cancer cells throughout the body and destroy them. The company will organize an End-of-Phase 2 meeting with the FDA by the end of Q1 2012. With the FDA's guidance, the Company will move into a pivotal Phase 3 clinical development program in women with loco-regional breast cancer that express low to moderate levels of HER2. Read more ?

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