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ǰǾǰó(ó ) ǰǾǰ򰡿 3D ̿ ǰ ߿ ʿ ֿ 3D ̿ ǰ -ü ǰ ̵Ρ ߰ߴٰ .
ֿ 3D ̿ ǰ -ü ǰ з ǰƯм ڷ ӻ ȿ 򰡽 ӻ ̴.

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20171218 ġ ̷ 翡 PD-L1 缺(TPS 50%) IV ̼ Ҽ ȯڸ Pembrolizumab + Ipilimumab Pembrolizumab + ϴ 3, , ߴ ӻ(KEYNOTE-598) 3 MK-3475
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NCT Number Title Conditions Interventions Sponsor
Collaborators
Phases
NCT03387098 QUILT-3.070: NANT Pancreatic Cancer Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy Pancreatic Cancer Drug: Aldoxorubicin HCl|Biological: ALT-803|Biological: ETBX-011|Biological: GI-4000|Biological: haNK for infusion|Biological: avelumab|Biological: bevacizumab
......
NantKwest, Inc. Phase 1
Phase 2
NCT03368729 Niraparib in Combination With Trastuzumab in Metastatic HER2+ Breast Cancer Metastatic Breast Cancer|HER2 Positive Breast Carcinoma Drug: Niraparib|Drug: Trastuzumab University of Alabama at Birmingham
Translational Breast Cancer Research Consortium|
Phase 1
Phase 2
NCT03088878 A Study of the Cirmtuzumab and Ibrutinib in Patients With B-Cell Lymphoid Malignancies B-cell Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Mantle Cell Lymphoma Drug: Cirmtuzumab|Drug: Ibrutinib|Drug: Cirmtuzumab plus ibrutinib University of California, San Diego Oncternal Therapeutics, Inc Phase 1
Phase 2
NCT03368859 A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine/Oxaliplatin and Bevacizumab Cancer - Metastatic Colorectal Drug: ABT-165|Drug: Bevacizumab|Drug: Irinotecan|Drug: Leucovorin|Drug: Fluorouracil - bolus|Drug: Fluorouracil - infusion AbbVie Phase 2
NCT03367715 Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma MGMT-unmethylated Glioblastoma (GBM)|GBM Drug: Nivolumab|Drug: Ipilimumab|Radiation: Radiation Therapy (RT) New York University School of Medicine Phase 2
NCT03272633 Irradiated Donor Cells Following Stem Cell Transplant in Controlling Cancer in Patients With Hematologic Malignancies Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia in Remission|Hematopoietic Cell Transplantation Recipient|JAK2 Gene Mutation|Loss of Chromosome 17p|Mantle Cell Lymphoma|Minimal Residual Disease..... Procedure: Allogeneic Hematopoietic Stem Cell Transplantation|Biological: Irradiated Allogeneic Cells... Rutgers, The State University of New Jersey|National Cancer Institute (NCI) Phase 2
NCT03358706 A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Moderate to Severe Crohn's Disease Crohn Disease Drug: Ustekinumab IV Infusion|Drug: Ustekinumab SC Injection|Drug: Midazolam 2 mg|Drug: Warfarin 10 mg|Drug: Vitamin K 10 mg|Drug: Omeprazole 20 mg|Drug: Dextromethorphan 30 mg|Drug: Caffeine 100 mg Janssen Research & Development, LLC Phase 1
 

NCT Number Title Conditions Interventions Sponsor
/Collaborators
Phases
NCT03295383 Randomized Clinical Trial Comparing the Safety and Efficacy of Rituximab Versus Oral Cyclophosphamide in Severe Forms of Mucous Membrane Pemphigoid Severe Forms of Mucous Membrane Pemphigoid Drug: Rituximab 1g IV|Drug: Cyclophosphamide 50Mg Oral Tablet|Drug: Placebo of Rituximab|Drug: Placebo Oral Tablet University Hospital, Rouen Phase 3
NCT03387046 A Pilot Study in Subjects With Relapsing Remitting Multiple Sclerosis (RR-MS) Multiple Sclerosis, Relapsing-Remitting Dietary Supplement: D-aspartate
Drug: Placebo
Biological: IFN beta-1a
Drug: Methylprednisolone
Merck KGaA Phase 2
NCT03358706 A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Moderate to Severe Crohn's Disease Crohn Disease Drug: Ustekinumab IV Infusion|Drug: Ustekinumab SC Injection|Drug: Midazolam 2 mg|Drug: Warfarin 10 mg|Drug: Vitamin K 10 mg|Drug: Omeprazole 20 mg|Drug: Dextromethorphan 30 mg|Drug: Caffeine 100 mg Janssen Research & Development, LLC Phase 1
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NCT Number Title Conditions Interventions Sponsor
/Collaborators
Phases
NCT03380689 Phase I Study of Biweekly SIRB Regimen for Metastatic Colorectal Cancer Metastatic Colorectal Cancer Drug: S-1|Drug: Irinotecan|Drug: Bevacizumab Fujian Cancer Hospital Phase 1
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306ȣ (2018.1.2.)
Vol. 68 (January 15, 2018)

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